A drug prescribed for decades to help reduce blood pressure may develop into an important treatment for MS, say researchers at Oxford University.
Amiloride was found to reduce degeneration of nerve tissue in mice by limiting the amount of calcium entering cells and the research team are now planning a trial in MS patients. However, Professor Lars Fugger from the Medical Research Council Human Immunology Unit said that progress will be slow.
“To develop a drug from scratch takes 10-15 years and a billion dollars and some of them are abruptly halted by unexpected side effects”, he warned.by Joshua Harris